Topology Data Bank of Transmembrane Proteins
Topology, Structure and Prediction.

Database status

Database release: v3.3
Release date: 2025-01-12
Entries: 9588
Topology data: 685414
Alpha helical proteins: 9310
Beta barrel proteins: 279
PubMed links: 43320
PDB links: 31246
Visitors: 1014588

Membrane definition

Prokaryotic cell

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Cell outer membrane

The prokaryotic outer cell membrane is the selectively permeablemembrane which separates the prokaryotic periplasm from its cellsurroundings. Traditionally only Gram-negative bacteria were thoughtof as having an outer membrane, but recent work has shown someActinobacteria, including Mycobacterium tuberculosis, as well as atleast 1 archaea (Ignicoccus hospitalis) have a cell outer membrane

  • Outside: Extracellular
  • Inside: Periplasmic space